Regulation of Voltage-Activated K+ Channel Gating by Transmembrane β Subunits
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چکیده
منابع مشابه
Regulation of Voltage-Activated K+ Channel Gating by Transmembrane β Subunits
Voltage-activated K(+) (K(V)) channels are important for shaping action potentials and maintaining resting membrane potential in excitable cells. K(V) channels contain a central pore-gate domain (PGD) surrounded by four voltage-sensing domains (VSDs). The VSDs will change conformation in response to alterations of the membrane potential thereby inducing the opening of the PGD. Many K(V) channel...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2012
ISSN: 1663-9812
DOI: 10.3389/fphar.2012.00063